Publications
A consistency-based consensus algorithm for de novo and reference-guided sequence assembly of short reads
Rausch T, Koren S, Denisov G, Weese D, Emde AK, D枚ring A, Reinert K
PMID:
Abstract
Novel high-throughput sequencing technologies pose new algorithmic challenges in handling massive amounts of short-read, high-coverage data. A robust and versatile consensus tool is of particular interest for such data since a sound multi-read alignment is a prerequisite for variation analyses, accurate genome assemblies and insert sequencing.