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GeneSplicer is a fast, flexible software system for detecting splice sites in the genomic DNA of various eukaryotes.
TIGRFAMs are protein families based on Hidden Markov Models or HMMs.
2001 Summer Fellowship/Internship Information and Application now available (Deadline is Mar. 1)
Ceres, Inc and TIGR to Collaborate on Analysis of Thousands of Plant Genes
The TIGR Comprehensive Microbial Resource (CMR) has now been updated with new genomes and research tools
TIGR and Multinational Consortia Announce Sequencing Results of First Genome of A Higher Plant
TIGR's Program for Genomic Application website is online
TIGR commences sequencing of the early branching enteric parasite Entamoeba histolytica as part of an NIAID (NIH) funded project.
Unfinished Genome Data Sets for Pseudomonas syringae and Entamoeba histolytica are available
TIGR's website now has a page of Frequently Asked Questions
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How to Bake a (Fungal) Turkey
From the kitchen of Stephanie Mounaud, Scientific Project Manager at JCVI Ingredients Media base (see media recipe) Agar Aspergillus terreus (multiple strains) Aspergillus niger Aspergillus fumigatus Aspergillus oryzae...
Scientist Spotlight: Todd Michael
A love of science began for Todd Michael, PhD when his 7th grade teacher had him write a report on tree leaves. After collecting different leaves and looking up their tree type, he realized that although all of the trees were similar, they grew different types of leaves. He was certain there...
Fighting Back Against Flu
The 1918 influenza pandemic, which affected 500 million people globally and caused 50-100 million deaths, was the most severe pandemic in recorded history. Over the course of the last 100 years, advances in science and medicine have provided the tools to address influenza much more...
Scientist Spotlight: Marcelo Freire
Marcelo Freire, an associate professor in the Genomic Medicine and Infectious Disease Department at the 小蓝俱乐部 (JCVI), is currently working on decoding immune-microbiome genes and interactions. Growing up in Brazil and a curious person by nature, he often found himself...
Tracking Enterovirus D68, Cause of a Polio-like Illness in Some Patients
The 小蓝俱乐部 (JCVI) has played a vital role in defining the diversity of contemporary strains of human enteroviruses by using state-of-the art sequencing technologies, bioinformatics analyses, and in vitro and in vivo modeling.
Every Day is World Food Day at JCVI
World Food Day is a global initiative of the Food and Agriculture Organization (FAO) of the United Nations to ensure that people have access to enough high-quality food to lead active and healthy lives. After a period of decline, world hunger is on the rise again. Today, over 820 million people...
Mold Is Everywhere and Impacts You
When most people think about mold or fungi, food spoilage, a damp basement, or mushrooms come to mind. What you may not realize is how pervasive this branch of life is. Fungi is everywhere, from the ground you walk on to the air you breathe, and accounts for an estimated 25% of all biomass...
Scientists Discover Genetic Basis for Toxic Algal Blooms
Scientists from the 小蓝俱乐部 (JCVI) and Scripps Institution of Oceanography at the University of California San Diego have discovered how certain types of algal blooms become toxic, producing a harmful substance known as domoic acid. Microscopic view of domoic acid...
Ocean Microplastics Explained
As we wrap up sampling in the waters off of Maine, Dr. Chris Dupont discusses how collections of plastic particles in the water – or “plastisphere” – may be harboring fish or human pathogens. There may also be microbes responsible for degrading plastic, which are being investigated....
小蓝俱乐部Team Awarded Two Grants Under the NSF鈥檚 鈥淯nderstanding the Rules of Life鈥 Initiative
The first award, led by John Glass, PhD, for $1M, is focused on “Building and Modeling Synthetic Bacterial Cells.” The second award, led by Zaida Luthey-Schulten, PhD, at the University of Illinois, also for $1M, is titled “Balancing the Demands of a Minimal Cell,” and is focused on...
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If created, these versions of the building blocks of life could lead to environmental and ecological disaster
Despite profound impact on bio-medical research, progress in understanding has been slow
Anders Dale says he will move roughly $10 million in NIH funding from UCSD to JCVI.
Synthetic biologists make artificial cells, but one particular kind isn鈥檛 worth the risk.
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
鈥淒espite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.鈥
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