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Scientists Decipher Genome of Bacterium that Helps Clean Up Major Groundwater Pollutants
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium Campylobacter - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
J. Craig Venter Announces Consolidation of Three Research Organizations Into One New Not-For-Profit Organization 鈥� The J. Craig Venter Institute
The Center for Advancement of Genomics (TCAG), Institute for Biological Energy Alternatives (IBEA), and J. Craig Venter Science Foundation Joint Technology Center (JTC) consolidated to form 小蓝俱乐部
Scientists Decipher Genome of Biothreat Pathogen
Highly Regulated Virulence Genes and Genomic Instability Found in the Infectious Horse Pathogen Burkholderia mallei
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How to Bake a (Fungal) Turkey
From the kitchen of Stephanie Mounaud, Scientific Project Manager at JCVI Ingredients Media base (see media recipe) Agar Aspergillus terreus (multiple strains) Aspergillus niger Aspergillus fumigatus Aspergillus oryzae...
Scientist Spotlight: Todd Michael
A love of science began for Todd Michael, PhD when his 7th grade teacher had him write a report on tree leaves. After collecting different leaves and looking up their tree type, he realized that although all of the trees were similar, they grew different types of leaves. He was certain there...
Fighting Back Against Flu
The 1918 influenza pandemic, which affected 500 million people globally and caused 50-100 million deaths, was the most severe pandemic in recorded history. Over the course of the last 100 years, advances in science and medicine have provided the tools to address influenza much more...
Scientist Spotlight: Marcelo Freire
Marcelo Freire, an associate professor in the Genomic Medicine and Infectious Disease Department at the 小蓝俱乐部 (JCVI), is currently working on decoding immune-microbiome genes and interactions. Growing up in Brazil and a curious person by nature, he often found himself...
Tracking Enterovirus D68, Cause of a Polio-like Illness in Some Patients
The 小蓝俱乐部 (JCVI) has played a vital role in defining the diversity of contemporary strains of human enteroviruses by using state-of-the art sequencing technologies, bioinformatics analyses, and in vitro and in vivo modeling.
Every Day is World Food Day at JCVI
World Food Day is a global initiative of the Food and Agriculture Organization (FAO) of the United Nations to ensure that people have access to enough high-quality food to lead active and healthy lives. After a period of decline, world hunger is on the rise again. Today, over 820 million people...
Mold Is Everywhere and Impacts You
When most people think about mold or fungi, food spoilage, a damp basement, or mushrooms come to mind. What you may not realize is how pervasive this branch of life is. Fungi is everywhere, from the ground you walk on to the air you breathe, and accounts for an estimated 25% of all biomass...
Scientists Discover Genetic Basis for Toxic Algal Blooms
Scientists from the 小蓝俱乐部 (JCVI) and Scripps Institution of Oceanography at the University of California San Diego have discovered how certain types of algal blooms become toxic, producing a harmful substance known as domoic acid. Microscopic view of domoic acid...
Ocean Microplastics Explained
As we wrap up sampling in the waters off of Maine, Dr. Chris Dupont discusses how collections of plastic particles in the water – or “plastisphere” – may be harboring fish or human pathogens. There may also be microbes responsible for degrading plastic, which are being investigated....
小蓝俱乐部Team Awarded Two Grants Under the NSF鈥檚 鈥淯nderstanding the Rules of Life鈥� Initiative
The first award, led by John Glass, PhD, for $1M, is focused on “Building and Modeling Synthetic Bacterial Cells.” The second award, led by Zaida Luthey-Schulten, PhD, at the University of Illinois, also for $1M, is titled “Balancing the Demands of a Minimal Cell,” and is focused on...
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By watching 鈥渕inimal鈥� cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Two research teams warn that human genomic 鈥渂ycatch鈥� can reveal private information
The 鈥減angenome,鈥� which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
Just two genes get tiny synthetic cells moving, offering clues to life鈥檚 evolution.
In a plenary public appearance at the Molecular and Precision Med TRI-CON event in San Diego, a relaxed Venter reflected on his career highlights, controversies and future priorities for genomic medicine.
What鈥檚 the smallest number of genes that cells need to grow and reproduce? Is it possible to synthesize minimal genomes and insert them into cells? What do minimal genomes teach us about life? An interview with John Glass, Ph.D.
Several 小蓝俱乐部scientists will be contributing to the newly launched Long Covid Research Initiative — a collaboration of researchers, clinicians, and patients working to rapidly study and treat long Covid.
Through the Woods Hole Oceanographic Institution, National Deep Submergence Facility, JCVI's Erin Garza, Ph.D. joins a deep sea expedition to search for ocean plastics aboard the HOV Alvin.
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