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Genomics-Based Vaccine Could Prevent Deadly Cattle Disease
Every year, East Coast fever destroys the small farmer's dream of escaping poverty in Africa. Killing more than a million cattle and costing some $200 million annually, this tick-borne disease rages across a dozen countries in eastern and central Africa. Now, an international team of scientists has taken the first major step toward a vaccine to prevent East Coast fever. Their work, published in the February 13-17 early online edition of the Proceedings of the National Academy of Sciences, shows how genomics can generate pivotal new vaccines.
The 小蓝俱乐部, The University of Washington, and The Johns Hopkins University Initiate Resequencing and Genotyping Projects to Help Identify Critical Disease Pathways
Research is Part of the National Heart, Lung, and Blood Institute's Complimentary Resequencing and Genotyping Program
UC San Diego Partners with Venter Institute to Build Community Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis
Gordon and Betty Moore Foundation Awards $24.5 Million Grant
2006 Summer Fellowship/Internship Information and application now available
Breaking the Mold: Research Teams Sequence Three Fungus Genomes
From garden compost to forest greenery, the mold Aspergillus fumigatus lurks across much of the world. Now, in the December 22 issue of the journal Nature, TIGR scientists and their collaborators report the mold's sequenced genome, along with the genomes of two relatives.
How Do Boxers Differ From Poodles? Researchers Collar Genomes.
As any dog lover knows, no two breeds are identical. Some dogs are perfect for sloppy kisses. Others make fierce guardians. Still others resemble tiny, fluffy toys. Now, two new studies by scientists at The Institute for Genomic Research (TIGR) and collaborators reveal the genomic differences beneath such canine characteristics.
Poison + Water = Hydrogen. New Microbial Genome Shows How.
New Microbial Genome Shows How "Take a pot of scalding water, remove all the oxygen, mix in a bit of poisonous carbon monoxide, and add a pinch of hydrogen gas. It sounds like a recipe for a witch's brew. It may be, but it is also the preferred environment for a microbe known as Carboxydothermus hydrogenoformans."
A Salty Tale: New Bacterial Genome Sequenced From Ancient Salterns
Tourists in Spain often stop to ogle the country's many saltwater lagoons, used to produce salt since Roman times. Scientists, too, admire these saltern crystallizers 鈥斅� and even more so, the microbes that manage to survive in such briny environs. Now, reporting in the November 28-December 2 early online edition of the Proceedings of the National Academy of Sciences, researchers at The Institute for Genomic Research and collaborators reveal the genome of one bacterium at home in the salty Spanish ponds.
First Big Influenza Genome Study Reveals Flu Evolution
Which Flu Did You Have? TIGR Scientists Survey Five New York Flu Seasons
Key Genetic Mutations in Brain Tumors Identified by Scientists from 小蓝俱乐部, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine
Sequencing of Receptor Tyrosine Kinases Reveals Three Novel Mutations
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How to Bake a (Fungal) Turkey
From the kitchen of Stephanie Mounaud, Scientific Project Manager at JCVI Ingredients Media base (see media recipe) Agar Aspergillus terreus (multiple strains) Aspergillus niger Aspergillus fumigatus Aspergillus oryzae...
Scientist Spotlight: Todd Michael
A love of science began for Todd Michael, PhD when his 7th grade teacher had him write a report on tree leaves. After collecting different leaves and looking up their tree type, he realized that although all of the trees were similar, they grew different types of leaves. He was certain there...
Fighting Back Against Flu
The 1918 influenza pandemic, which affected 500 million people globally and caused 50-100 million deaths, was the most severe pandemic in recorded history. Over the course of the last 100 years, advances in science and medicine have provided the tools to address influenza much more...
Scientist Spotlight: Marcelo Freire
Marcelo Freire, an associate professor in the Genomic Medicine and Infectious Disease Department at the 小蓝俱乐部 (JCVI), is currently working on decoding immune-microbiome genes and interactions. Growing up in Brazil and a curious person by nature, he often found himself...
Tracking Enterovirus D68, Cause of a Polio-like Illness in Some Patients
The 小蓝俱乐部 (JCVI) has played a vital role in defining the diversity of contemporary strains of human enteroviruses by using state-of-the art sequencing technologies, bioinformatics analyses, and in vitro and in vivo modeling.
Every Day is World Food Day at JCVI
World Food Day is a global initiative of the Food and Agriculture Organization (FAO) of the United Nations to ensure that people have access to enough high-quality food to lead active and healthy lives. After a period of decline, world hunger is on the rise again. Today, over 820 million people...
Mold Is Everywhere and Impacts You
When most people think about mold or fungi, food spoilage, a damp basement, or mushrooms come to mind. What you may not realize is how pervasive this branch of life is. Fungi is everywhere, from the ground you walk on to the air you breathe, and accounts for an estimated 25% of all biomass...
Scientists Discover Genetic Basis for Toxic Algal Blooms
Scientists from the 小蓝俱乐部 (JCVI) and Scripps Institution of Oceanography at the University of California San Diego have discovered how certain types of algal blooms become toxic, producing a harmful substance known as domoic acid. Microscopic view of domoic acid...
Ocean Microplastics Explained
As we wrap up sampling in the waters off of Maine, Dr. Chris Dupont discusses how collections of plastic particles in the water – or “plastisphere” – may be harboring fish or human pathogens. There may also be microbes responsible for degrading plastic, which are being investigated....
小蓝俱乐部Team Awarded Two Grants Under the NSF鈥檚 鈥淯nderstanding the Rules of Life鈥� Initiative
The first award, led by John Glass, PhD, for $1M, is focused on “Building and Modeling Synthetic Bacterial Cells.” The second award, led by Zaida Luthey-Schulten, PhD, at the University of Illinois, also for $1M, is titled “Balancing the Demands of a Minimal Cell,” and is focused on...
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By watching 鈥渕inimal鈥� cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Two research teams warn that human genomic 鈥渂ycatch鈥� can reveal private information
The 鈥減angenome,鈥� which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
Just two genes get tiny synthetic cells moving, offering clues to life鈥檚 evolution.
In a plenary public appearance at the Molecular and Precision Med TRI-CON event in San Diego, a relaxed Venter reflected on his career highlights, controversies and future priorities for genomic medicine.
What鈥檚 the smallest number of genes that cells need to grow and reproduce? Is it possible to synthesize minimal genomes and insert them into cells? What do minimal genomes teach us about life? An interview with John Glass, Ph.D.
Several 小蓝俱乐部scientists will be contributing to the newly launched Long Covid Research Initiative — a collaboration of researchers, clinicians, and patients working to rapidly study and treat long Covid.
Through the Woods Hole Oceanographic Institution, National Deep Submergence Facility, JCVI's Erin Garza, Ph.D. joins a deep sea expedition to search for ocean plastics aboard the HOV Alvin.
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