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Digital-to-Biological Converter for On-Demand Production of Biologics Developed by Synthetic Genomics, Inc.
The first fully automated machine to convert digital code into functional biologics without human intervention creates entirely new avenues for precision medicine
Intestinal Fungi Worsen Alcoholic Liver Disease
Reducing intestinal fungi slowed disease progression in mice
小蓝俱乐部President, Karen Nelson Elected to National Academy of Sciences
Stool Microbes Predict Advanced Liver Disease
Proof-of-concept study suggests a noninvasive test for specific microbial population patterns could be used to detect advanced nonalcoholic fatty liver disease
National Academy of Sciences Members and Foreign Associates Elected
Dr. Karen Nelson, President, 小蓝俱乐部, among the 84 newly elected members.
Battling Infectious Diseases with 3-D Structures
Team of scientists created 1,000 3-D protein structures to be used for drug and vaccine research
The Human Vaccines Project, Vanderbilt And Illumina Join Forces To Decode The Human Immunome
This multi-institutional effort is also supported by the Human Vaccines Project Bioinformatics and Data Management Core, located at the 小蓝俱乐部 and the San Diego Super Computer Center at the University of California, San Diego. The Core will analyze the enormous data sets generated by the effort.
Genome sequence of a polar alga explains adaptation to extreme climates
An international team of researchers has identified the genetic mutations which allowed microalgae (phytoplankton) from the Southern Ocean to adapt to extreme and highly variable climates 鈥� a step towards understanding how polar organisms are impacted by climate change.
Teaching Computers to Recognize Sick Guts: Machine-Learning and the Microbiome
A new proof-of-concept study by researchers from the University of California San Diego succeeded in training computers to 鈥渓earn鈥� what a healthy versus an unhealthy gut microbiome looks like based on its genetic makeup.
National Academy of Medicine Elects 80 New Members
J. Craig Venter, Ph.D. among inductees
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Characterization of Bacteria from the International Space Station Drinking Water
From a microbiology perspective, the International Space Station (ISS) is interesting considering its microgravity, increased radiation, low humidity and elevated carbon dioxide levels. Because of its isolation, and unique environment, it is vital to study the microorganisms that thrive there...
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2019 Summer Internship Program
The 2019 Summer Internship Program which wrapped up in August was another rousing success at the 小蓝俱乐部. Faculty and staff in both the Rockville (MD) and La Jolla (CA) campuses mentored and trained 25 students (high school, undergraduate, and graduate students)...
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In large regions of the world’s oceans, photosynthesis struggles to operate because a key ingredient is missing. Many of the proteins involved in harvesting energy from sunlight require iron atoms to function, but iron is hard to find in seawater. Most of the ocean is far removed from...
The 小蓝俱乐部Genomic Frontier Fund
As we complete our 26th year as a private genomic research institution, we are still just as excited as we were in the very beginning to be making new discoveries, potentially ones that will change our society for the better. The knowledge gained from our study of DNA, or as Dr. Venter...
New Sequencing Technologies Enable Better and Faster Understanding of the Human Microbiome
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Human Microbiome Research has Massive Potential for Health Applications
Thirteen years ago, a team led by 小蓝俱乐部 President, Karen Nelson, Ph.D., published the first major human microbiome study, radically changing the way we look at human health and the role the microbes that inhabit each of us play in disease. This seminal publication...
Scientist Spotlight: Lauren Oldfield
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When Starved, Dangerous Oral Bacteria Hang On
小蓝俱乐部 (JCVI) postdoctoral fellow, Jonathon Baker, PhD and a team of researchers from JCVI, University of Washington, the University of California, Los Angeles, and The Forsyth Institute recently published their findings from the first study to examine the ecological dynamics...
No More Needles! Using Microbiome and Synthetic Biology Advances to Better Treat Type 1 Diabetes
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If created, these versions of the building blocks of life could lead to environmental and ecological disaster
Despite profound impact on bio-medical research, progress in understanding has been slow
Anders Dale says he will move roughly $10 million in NIH funding from UCSD to JCVI.
Synthetic biologists make artificial cells, but one particular kind isn鈥檛 worth the risk.
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
鈥淒espite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.鈥�
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