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Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
TIGR's informatics group today posted the third major release (3.0) of the genome annotation for the model plant Arabidopsis thaliana
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DNA microarrays vs RNAseq 鈥� The winner and new heavyweight champion is?... It鈥檚 a draw.
In the past year or so there have been several articles stating that the death of microarray technology is growing near. These proclamations are due to the more recently introduced methodology referred to as RNAseq. At first glance I wrote these claims off as being silly and premature. Over...
Science Festivals
With spring around the corner (or at least we hope), there are several upcoming science festivals. These festivals are designed to provide students and families opportunities to find out what is happening in local science research institutes, universities and companies. These organizations...
Waste-to-Electricity?
Many of us don’t spend a lot of time pondering wastewater treatment unless we absolutely have to. However, we may need to start rethinking this dirty job. In the United States wastewater treatment is a multi-billion dollar industry that is facing major challenges in the...
300 Papers
Congratulations to Ken Nealson for publishing his 300th paper! Ken has been a driving force in microbiology for 40 years having published several seminal papers in microbial ecology. In the 1980s he helped to pioneer the field of geobiology and discovered bacteria that thrive on metal. Dr....
2010 Internship Program Ready to Go
Are you thinking about summer already? We are!! The 2010 Summer Internship Program is open to accept applications. Last year, we received and reviewed over 300 applications from all over the US and the world for our summer program. Interns were selected to work in most of the research groups...
Scientist Spotlight: Karen Nelson
Karen’s interest in the natural world was sparked at a young age. Born in Jamaica, she enjoyed the outdoors and wonders of nature. Karen was drawn to animals and wanted to become a veterinarian, but after taking some human and animal nutrition courses in college she was hooked on...
Antarctic Epiblog: Leaving McMurdo
Ice formation outside McMurdo Station After we took our samples out at the ice edge, we returned to McMurdo Station for several intense days of demobilization. We had to return all of the large drills, power equipment and camping gear, and spent a considerable time preparing our...
Station IV: The Ice Edge
Our last station in our Ross Sea transect was out at the ice edge, about two miles north of our previous station, Station III. We were interested to see how plankton in the open polynya were different from the phytoplankton we isolated from areas locked in sea-ice. Polynyas are ice-free areas...
Station III: approaching the ice edge
As we were finishing up our work at Station II, we called MacOps, the radio command center for McMurdo Station, and got a 24 hour weather update: a high to the north of Ross Island was blocking a storm in the south, and we were caught in the middle. The prediction: snow, and lots of it. We had...
Station II, Inaccessible Island
The second storm of our trip hit us while we were packing up Station I for a return to McMurdo. The winds began gusting over 50 miles per hour, and the visibility dropped to near zero. We had already packed up camp, but the orders came in over the radio that Condition 1 had been imposed on the...
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If created, these versions of the building blocks of life could lead to environmental and ecological disaster
Despite profound impact on bio-medical research, progress in understanding has been slow
Anders Dale says he will move roughly $10 million in NIH funding from UCSD to JCVI.
Synthetic biologists make artificial cells, but one particular kind isn鈥檛 worth the risk.
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
鈥淒espite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.鈥�
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