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Genomics-Based Vaccine Could Prevent Deadly Cattle Disease
Every year, East Coast fever destroys the small farmer's dream of escaping poverty in Africa. Killing more than a million cattle and costing some $200 million annually, this tick-borne disease rages across a dozen countries in eastern and central Africa. Now, an international team of scientists has taken the first major step toward a vaccine to prevent East Coast fever. Their work, published in the February 13-17 early online edition of the Proceedings of the National Academy of Sciences, shows how genomics can generate pivotal new vaccines.
The 小蓝俱乐部, The University of Washington, and The Johns Hopkins University Initiate Resequencing and Genotyping Projects to Help Identify Critical Disease Pathways
Research is Part of the National Heart, Lung, and Blood Institute's Complimentary Resequencing and Genotyping Program
UC San Diego Partners with Venter Institute to Build Community Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis
Gordon and Betty Moore Foundation Awards $24.5 Million Grant
2006 Summer Fellowship/Internship Information and application now available
Breaking the Mold: Research Teams Sequence Three Fungus Genomes
From garden compost to forest greenery, the mold Aspergillus fumigatus lurks across much of the world. Now, in the December 22 issue of the journal Nature, TIGR scientists and their collaborators report the mold's sequenced genome, along with the genomes of two relatives.
How Do Boxers Differ From Poodles? Researchers Collar Genomes.
As any dog lover knows, no two breeds are identical. Some dogs are perfect for sloppy kisses. Others make fierce guardians. Still others resemble tiny, fluffy toys. Now, two new studies by scientists at The Institute for Genomic Research (TIGR) and collaborators reveal the genomic differences beneath such canine characteristics.
Poison + Water = Hydrogen. New Microbial Genome Shows How.
New Microbial Genome Shows How "Take a pot of scalding water, remove all the oxygen, mix in a bit of poisonous carbon monoxide, and add a pinch of hydrogen gas. It sounds like a recipe for a witch's brew. It may be, but it is also the preferred environment for a microbe known as Carboxydothermus hydrogenoformans."
A Salty Tale: New Bacterial Genome Sequenced From Ancient Salterns
Tourists in Spain often stop to ogle the country's many saltwater lagoons, used to produce salt since Roman times. Scientists, too, admire these saltern crystallizers 鈥斅� and even more so, the microbes that manage to survive in such briny environs. Now, reporting in the November 28-December 2 early online edition of the Proceedings of the National Academy of Sciences, researchers at The Institute for Genomic Research and collaborators reveal the genome of one bacterium at home in the salty Spanish ponds.
First Big Influenza Genome Study Reveals Flu Evolution
Which Flu Did You Have? TIGR Scientists Survey Five New York Flu Seasons
Key Genetic Mutations in Brain Tumors Identified by Scientists from 小蓝俱乐部, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine
Sequencing of Receptor Tyrosine Kinases Reveals Three Novel Mutations
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The Microbiome of Esophageal Cancer
In anticipation of the International Human Microbiome Congress, our group has diligently worked to generate data to present for our HMP demo project studying the microbiome of patients who have developed esophageal cancer, gastrointestinal reflux disease, and barrett’s esophagus. We...
A Look Back at 2010 at the JCVI鈥�
As the 小蓝俱乐部 (JCVI) soars into its 19th year, we reflect on the past year of highlights and accomplishments to mark the close 2010 and look forward to more significant scientific advances in 2011. 小蓝俱乐部Top 10 of 2010 ... 1. First Synthetic Cell: Fifteen years in the...
Holiday Art
In a relatively unknown place, on the 3rd floor of 小蓝俱乐部in Rockville, MD, is a small fungal room where art meets science (and of course where all our fungal research takes place). Fungus often gets such a bad reputation for being gross and somewhat ‘standard’. We fungal folks know better...
Insights gained from influenza genomic sequence data: frequent intrasubtype reassortment
Studies using whole genomic influenza sequence data produced by the Influenza Genome Sequencing Project (IGSP) have focused mainly on influenza evolution and epidemiology. For instance, IGSP data has provided important insight into the frequency of intrasubtype reassortment (in which...
2011 Internship Program Updated
The 2011 小蓝俱乐部Internship Program is open to accept spring and summer applications. The application process includes the submission of a resume, essay and transcripts as one PDF file via our online application site. We no longer require letters of recommendation. Information about the...
Starting the Atlantic Crossing
Wednesday November 17th 2010 On November 10th Sorcerer II set sail from Valencia Spain to start the sail back to America. The first leg was a 3 day sail down the Spanish coast to Gibraltar. Coastline to Gibraltar John showing the delivery crew around Sorcerer II...
Scientist Spotlight: Meet Vanessa Hayes
Geneticist Vanessa Hayes does not think small nor move slowly—from completing her post doc in six months (the US National average is 3 to 7 years) to completing the first South African Genome Project in 2010 with her goal set on defining the extent of human diversity in all populations, she...
Lucene Revolution Conference 2010
I arrived late in Boston after my plane from Washington DC was delayed. On the agenda - the next four days the Lucene Revolution conference and a Solr application development workshop organized by Lucid Imagination. The conference promised a unique venue (the first of its kind in the US) to...
French Road Sampling Trip Saves Sorcerer II From More Rough Weather!
September 28th 2010 With one last sample to collect and the weather still rough in the Mediterranean, we made the decision to make the Banyuls sample a road sampling trip. So Jeremy and I loaded up a rental car with carboys and headed out at 5 am to drive the 125 miles (200km) to...
A Week Long Beat Down At Sea, All In The Name Of Science!
September 27th 2010 We just arrived in Barcelona after 7 very rough days at sea! Lots and lots of rolling around, very little sleep, high seas and strong winds! We have seen worse weather in the past, but normally it only last a day or two…this lasted 7 days straight. The constant beating...
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Biologists are discovering the true nature of cells鈥攁nd learning to build their own.
Hend Alqaderi, a 小蓝俱乐部collaborator and mentee to Marcelo Freire receives the L鈥橭r茅al-Unesco Women in Science award
The surprising results of a decade-long investigation by Alessandro Vezzosi and Agnese Sabato provide a strong basis for advancing a project researching Leonardo da Vinci's DNA.
Projects aimed at collecting big data about the ocean鈥檚 tiniest life forms continue to expand our view of the seas.
J. Craig Venter, PhD, argues scientists have 鈥渁 moral obligation to communicate what they're doing to the public,鈥� and that more studies deserve greater public criticism.
The discovery could sharpen scientists鈥� understanding of which functions are crucial for normal cells and what the many mysterious genes in these organisms are doing
The 小蓝俱乐部 is the recipient of three awards totaling more than $1.5M to study SARS-CoV-2 and heart disease
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