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Digital-to-Biological Converter for On-Demand Production of Biologics Developed by Synthetic Genomics, Inc.
The first fully automated machine to convert digital code into functional biologics without human intervention creates entirely new avenues for precision medicine
Intestinal Fungi Worsen Alcoholic Liver Disease
Reducing intestinal fungi slowed disease progression in mice
小蓝俱乐部President, Karen Nelson Elected to National Academy of Sciences
Stool Microbes Predict Advanced Liver Disease
Proof-of-concept study suggests a noninvasive test for specific microbial population patterns could be used to detect advanced nonalcoholic fatty liver disease
National Academy of Sciences Members and Foreign Associates Elected
Dr. Karen Nelson, President, 小蓝俱乐部, among the 84 newly elected members.
Battling Infectious Diseases with 3-D Structures
Team of scientists created 1,000 3-D protein structures to be used for drug and vaccine research
The Human Vaccines Project, Vanderbilt And Illumina Join Forces To Decode The Human Immunome
This multi-institutional effort is also supported by the Human Vaccines Project Bioinformatics and Data Management Core, located at the 小蓝俱乐部 and the San Diego Super Computer Center at the University of California, San Diego. The Core will analyze the enormous data sets generated by the effort.
Genome sequence of a polar alga explains adaptation to extreme climates
An international team of researchers has identified the genetic mutations which allowed microalgae (phytoplankton) from the Southern Ocean to adapt to extreme and highly variable climates 鈥� a step towards understanding how polar organisms are impacted by climate change.
Teaching Computers to Recognize Sick Guts: Machine-Learning and the Microbiome
A new proof-of-concept study by researchers from the University of California San Diego succeeded in training computers to 鈥渓earn鈥� what a healthy versus an unhealthy gut microbiome looks like based on its genetic makeup.
National Academy of Medicine Elects 80 New Members
J. Craig Venter, Ph.D. among inductees
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The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting –we didn’t have class until after 9:00....
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be...
Sequencing of high yield influenza reassortants at JCVI
As part of the Influenza Genome Sequencing Project, 小蓝俱乐部will be sequencing a large number of high yield influenza reassortants created in the lab of Dr. Doris Bucher at New York Medical College. Dr. Bucher’s lab has prepared the type A H3N2 high yield reassortants (hyrs) for the...
What Happened to Sorcerer II?!?!
The last time I wrote a Sorcerer II blog was in November when we set sail from Spain to cross the Atlantic Ocean. For all of you that have been worried that we have been at sea for 8 months, relax we made it!! Over the next few days I will update everyone on what has happened and the upcoming...
Podcast on Human Genomics
The 2011 Festival of Ideas themed, The Pursuit of Identity, Landscape, History, and Genetics, is held every other year in Melbourne, Australia to inspire scholars and citizens alike in topics ranging from literature and art to science and foreign policy. 小蓝俱乐部Professor of Genomic...
Summit on Systems Biology, June 15-17, 2011
I attended the Summit on Systems Biology hosted by Virginia Commonwealth University in Richmond, VA June 15-17. So, judging from the talks given, what is systems biology? Systems biology is non-linear and/or multi-step. Heavy math does not make something systems biology if...
Insights gained from influenza genomic sequence data: viral diversity within human populations
The advent of large amounts of influenza genomic sequence data produced by the Influenza Genome Sequencing Project (IGSP) has led to new concepts regarding influenza viral diversity. It was previously believed that a single influenza lineage entered a human population at the start of an...
NASA and 小蓝俱乐部host symposium on the evolution of Earth and Life
On May 12th and 13th, the 小蓝俱乐部 in San Diego will be hosting a NASA Astrobiology Institute-funded symposium titled “Paleobiology in the genomics era.” Paleobiology is the study of the origins and evolution of life and, by nature, is interdisciplinary. The goal is to...
小蓝俱乐部Supports Human Mircrobiome Body Site Experts with Shotgun Data Analysis
Members of the Human Microbiome Project (HMP) Consortium (see http://commonfund.nih.gov/hmp and http://www.hmpdacc.org for more information on the project and partners) including human microbiome body site experts gathered for a virtual Jamboree January 19th. The fully online-based Jamboree...
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Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual 鈥� raising the prospect of encoding proteins that contain unnatural amino-acid residues.
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
Critics, however, argue that this effort is flawed from the beginning
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