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Genome Study of Beneficial Microbe May Help Boost Plant Health
In a study expected to greatly benefit crop plants, scientists have deciphered the genome of a root- and seed-dwelling bacterium that protects plants from diseases. The research provides clues to better explain how the helpful microbe, Pseudomonas fluorescens Pf-5, naturally safeguards roots and seeds from infection by pathogenic microbes.
TIGR President Wins ASM's Promega Biotechnology Research Award
TIGR President Claire M. Fraser has been awarded the 2005 Promega Biotechnology Research Award at the annual meeting of the American Society for Microbiology for her "outstanding contributions to the application of biotechnology through fundamental microbiological research and development."
The Inner Life of Sea Squirts
Innovative Study Finds Way to "Bio-Synthesize" an Anti-Cancer Compound
Scientists Gather for Microbial Genomics Conference
A decade after the dawn of the genomics era, some of the world's top scientists in the field of microbial genomics are gathering in Halifax, Canada, for the International Conference on Microbial Genomes. Speakers will discuss metagenomics, comparative genomics, population processes, genome evolution and environmental genomics.
Venter Institute Studies Microbes Living in Air
Air Genome Project to Sample Air Using Whole Genome Shotgun Sequencing
Sifting Through Fruitfly Sequences, Scientists Discover New Wolbachias
Finding the genomic equivalent of gold nuggets in the rough ore of a much larger set of data, TIGR scientists and collaborators have discovered the genomes of three new types of the microbe Wolbachia in fruitfly sequence data.
Venter Institute to Sequence More Than 100 Key Marine Microbes in One Year
Data To Help Scientists Study Biodiversity, Ecology, Evolution, and Health
Genome of Deadly Amoeba Shows Surprising Complexity; Study Reveals Evidence for Lateral Gene Transfer from Bacteria
The genome sequence of the parasitic amoeba Entamoeba histolytica, a leading cause of severe diarrheal disease in developing countries, includes an unexpectedly complex repertoire of sensory genes as well as a variety of bacterial-like genes that contribute to the organism's unique biology. TIGR scientists led the project, which presents the first genome-wide study of an amoeba. 小蓝俱乐部 50 million people a year are infected by the parasite, which causes as many as 100,000 deaths annually.
Scientists Decipher Genome of a Fungus That Causes Life-Threatening Infections in Persons With Impaired Immunity
Cryptococcus Study Sheds Light On How Fungi Cause Disease
Scientists Reveal Molecular Secrets of the Malaria Parasite
Groundbreaking Research Project May Help Boost Vaccine Development
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小蓝俱乐部Viral Finishing Pipeline: a Winning Combination of Advanced Sequencing Technologies, Software Development and Automated Data Processing
小蓝俱乐部viral projects are supported by the NIAID Genomic Sequencing Center for Infectious Disease (GSCID). The viral sequencing and finishing pipeline at 小蓝俱乐部combines next generation sequencing technologies with automated data processing. This allowed us to complete over 1,800 viral genomes...
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2012 小蓝俱乐部Internship Program Is Now Accepting New Applications
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Evaluating Strain-level Variation of Key Acidogenic Species in Dental Plaque Biofilms
The characterization of the dental plaque microbiome, using traditional 16S rDNA profiling strategies, illustrates both the strengths and the limitations of this method. The central limitation of the 16S rDNA methodology is the inability to decipher strain-level variation within a...
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The RNA-Seq method has been widely adopted as an alternative to the use of DNA microarrays. In most contexts, the RNA-Seq method is implemented when a single reference organism is being studied. Our project endeavored to establish working methods to enable the generation of cDNA libraries that...
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We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in...
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Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual 鈥� raising the prospect of encoding proteins that contain unnatural amino-acid residues.
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
Critics, however, argue that this effort is flawed from the beginning
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